House holiday rentals in Panama
Find and book unique houses on Airbnb
Top-rated house rentals in Panama
Guests agree: these houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for house rentals in Panama
House rentals with a pool
Home in Panama
4.96 out of 5 average rating, 138 reviewsVilla Isabella in Coronado Beach Panama
Home in Bajo Boquete
4.8 out of 5 average rating, 111 reviewsSecluded Riverfront Home - Boquete area with Pool
Home in contadora
4.85 out of 5 average rating, 196 reviewsvilla in counter, pearls
Home in Panama City
4.81 out of 5 average rating, 32 reviewsBeautiful house with private pool
Home in Playa Mata Oscura
4.93 out of 5 average rating, 28 reviewsCasa De Ola, Jungle Beach Cabin
Home in Playa Venao
5.0 out of 5 average rating, 18 reviewsCasa Samambaia - sea view tropical paradise w pool
Home in San Carlos
4.93 out of 5 average rating, 89 reviewsBeach House-Ocean View Rooftop Jacuzzi & Pool
Home in Playa Bluff
5.0 out of 5 average rating, 18 reviewsJungle House 100m from the beach
Weekly house rentals
Home in Bocas del Toro
4.92 out of 5 average rating, 12 reviewsLa Casita Barrbra BnB
Home in Santa Catalina
4.97 out of 5 average rating, 29 reviewsCasa Colibrí - modern house in the green
Home in Nueva California
5.0 out of 5 average rating, 12 reviewsSpacious 3 bedroom house in Volcan cloud forest
Home in Bocas del Toro
5.0 out of 5 average rating, 21 reviewsTropical Paradise, Oceanfront Home in the Jungle
Home in Panamá
5.0 out of 5 average rating, 9 reviewsUnique 4 room house - direct access to the beach
Home in La Guaira
4.96 out of 5 average rating, 83 reviewsPuntita Manzanillo, fantastic sea and jungle
Home in Buenaventura, El Chirú
5.0 out of 5 average rating, 5 reviewsBuenaventura | Design & Privacy | Sleeps 12
Home in Bocas Del Toro
4.96 out of 5 average rating, 91 reviewsWiona of Villa Paraiso | Beachfront Villa & Pool
Private house rentals
Home in Bull Beach
5.0 out of 5 average rating, 13 reviewsYellowfin Casa 3
Home in Gamboa
4.86 out of 5 average rating, 88 reviewsBirdHouse@ Gamboa Panamá Canal
Home in Bocas del Toro
5.0 out of 5 average rating, 18 reviewsCasa del Fuego - Caribbean Beachfront Magic!
Home in San José
5.0 out of 5 average rating, 21 reviewsαlkeyler| Luxury Mini Resort 12 PERS @Punta Barco
Home in Playa Venao
5.0 out of 5 average rating, 13 reviewsNearly Oceanfront: Blue 3 Bedroom Spacious Villa
Home in David
4.97 out of 5 average rating, 65 reviewsBeautiful house in the heart of David.
Home in Veraguas Province
4.87 out of 5 average rating, 38 reviewsCasa Puerta al Mar with amaizing view, Morrillo
Home in Bajo Boquete
4.96 out of 5 average rating, 57 reviewsSpacious 3BR walking distance, close to everything
Destinations to explore
- Loft rentals Panama
- Rentals with a cinema Panama
- Holiday home rentals Panama
- Fitness-friendly rentals Panama
- Smoking-friendly rentals Panama
- Flat rentals Panama
- Villa rentals Panama
- Cottage rentals Panama
- Rentals with pools Panama
- Beach apartment rentals Panama
- Chalet rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Rentals with a patio Panama
- Family-friendly rentals Panama
- Bungalow rentals Panama
- Pet-friendly rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Family-friendly rentals Panama
- Waterfront rentals Panama
- Monthly Rentals Panama
- Farm stay rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Nature eco lodge rentals Panama
- Beach house rentals Panama
- Rentals with a sauna Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Rentals with beach access Panama
- Rentals with breakfast Panama
- Rentals with an accessible-height bed Panama
- Tiny house rentals Panama
- Treehouse rentals Panama
- Island rentals Panama
- Boutique hotel rentals Panama
- Townhouse rentals Panama
- Guest house rentals Panama
- Rentals with a washing machine and dryer Panama
- Rentals with a firepit Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Hotel rentals Panama
- Apartment rentals Panama
- Boat rentals Panama
- Bed and breakfasts Panama
- Rentals with a fireplace Panama
- Rentals with a hot tub Panama
- Wheelchair-accessible rentals Panama
- Rentals with lake access Panama
- House rentals Panama City
- Guest house rentals Panama City
- House rentals Playa Coronado
- House rentals Altos del Maria
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom